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RTS-1C Personal Bioreactor with Cooling

The Grant-bio RTS-1C is personal bioreactor with cooling which provides “Reverse-Spin” type of agitation and logging of microbial growth in 50 ml tubes in real time.

RTS-1C including TubeSpin® Bioreactor 50, TPP®, 20 pcs.


  • Innovative mixing due to reverse spinning of the sample around its own axis
  • Due to innovative mixing technology it is possible to measure optical density of the probe in real time
  • Software has been developed to store, display and analyse the data in real time
  • Compact device with low profile and small footprint for personal application
  • Temperature control allows use as an incubator, e.g. for cell growth
  • Active cooling and temperature profiling via software
  • The ability to change parameters such as temperature, RPM and “Reverse-Spin” frequency, allows to achieve consistency and reproducibility of results
  • Programmable Cycling/profiling of cultivation parameters such as temperature, RPM, “Reverse-Spin” frequency
  • The ability to remotely monitor the process of cultivation while home or using a mobile phone

Software features

  • Real–Time cell growth logging
  • 3D graphical representation of OD or growth rate over time over unit
  • Pause option
  • Save/Load option
  • Report option: PDF and Excel
  • Connect up to 12 units simultaneously to 1 computer
  • Remote monitoring option (requires internet connection)
  • Cycling/Profiling options
  • User calibration options for any microorganism


  • Bacterial cultivation with real time growth kinetics
  • Strain screening
  • Temperature stress and fluctuation experiments
  • Media screening and optimization
  • Synthetic and systems biology
  • Inhibition and toxicity tests
  • Strain quality control


* — Highest kLa (h-1) is achieved at 5 ml working volume which is optimal for aerobic cultivation
** — 850 to OD600 vary between strains and phases of growth
*** — Not guaranteed because OS not supported by producer

Dimensions (h x d x w)200 x 212 x 130mm
Theoretically possible measurement range in OD850 , at 10 ml working volume*: Rod shaped bacteria0-25 (0–45.6 OD600 equivalent**)
Theoretically possible measurement range in OD850 , at 10 ml working volume*: Yeast0-50 (0–75 OD600 equivalent)
E.coli BL21 Factory calibration measurement range, in OD850 : at 10–20 ml volume0 – 10 OD (0 – 19 OD600 equivalent)
E.coli BL21 Factory calibration measurement range, in OD850 : at 20–30 ml volume0 – 8 OD (0 – 15.2 OD600 equivalent)
Measurement wavelength (λ)850nm ± 15nm
Factory calibration measurement precision±0.3 OD 850
Mass transfer coefficient kLaUp to 350 ± 26 h-1 at 5ml
Light sourceLED (NIR Light diode)
Real time measurement1-60 minutes
Temperature setting range+4 to +70 (increment 0.1°C)
Bottom control range pointAmbient -15°C
Top control range point70°C
Temperature stability±0.1°C
Sample temperature accuracy:20 °C - 45°C: ±2 < 20°C: ±2 > 45°C: ±3
Sample temperature heating/cooling rate0.7°C/min
Sample volume5 – 30ml
Speed control range50 – 2000rpm (increment 10 rpm)
Speed control precision±15rpm
Reverse Spin Time1- 60 seconds (increment 1s)
Minimum PC requirementsIntel/AMD Processor, 1 GB RAM, Windows XP***/Vista/7/8/8.1/10, 2.0 USB port
Optimal PC requirementsIntel/AMD Processor, 3 GB RAM, Windows 7/8/8.1/10, 2.0 USB port
Power consumption60W (5A)
Input voltage12V dc
Nominal operating voltage120 - 230V (50/60Hz)

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